The Drug Metabolism Discussion Group have organised a stimulating and innovative series of sessions in this annual open meeting. The scientific program will consist of talks around Biotransformation, Virtual DMPK, PK/PD, Drug delivery challenges and many more including a debate on "Which is the most important DMPK function". The keynote address will be given by special guest Scott Obach. A DMDG clinic will also be held to discuss topics of mutual interest in a number of small breakout groups.