This, the 12th Florida Heterocyclic and Synthetic Conference, continues in the tradition of its highly successful predecessors. Registration will start on Sunday, March 6th with a Welcome Reception. On Monday the 7th through Wednesday the 9th, the Conference will feature eleven plenary lectures given by academic and industrial experts from around the world together with invited lectures and short courses on heterocyclic topics. A poster session combined with a buffet supper will be held on the evening of Monday, March 7th. A wine reception and conference banquet are scheduled for the evening of Tuesday, March 8th. The conference closes with a farewell party on the evening of Wednesday, March 9th.